CLL Therapy Goals
Know Your Goals Before You Choose a Treatment
Your doctor is an expert in oncology, but you’re an expert in you. By working together, you can create a list of treatment goals based on your specific needs, preferences, and situation.
Below are some ideas for goals that may be helpful as you go through your journey. Don’t feel like you need to take on all of them at once. Work through the process with your healthcare team at a pace that works for you.
Make it a goal
Understand Factors That May Affect Your Treatment Choice
There are many
for CLL. From how the treatment works to how long you need to take it, learn the specifics of each option. This will help you make an informed decision with your healthcare team and choose the treatment that’s right for you.1,2
The best therapy for each person may depend on many factors including2,3:
How to Talk About CLL With Your Doctor
Meeting with your doctor can be intimidating, especially at the beginning. You may want to write down your questions and concerns ahead of time so you don't forget anything.4
This discussion guide will help you plan ahead for each visit and cover important topics while you have your doctor's attention.
Download the discussion guide that's most relevant for you.
Make it a goal
Understand CLL Treatment Response Terminology
It is helpful to understand the terms you may find in your research or hear when you talk with your doctor about CLL. Here are some terms that may be used in discussions about your or a loved one’s response to CLL treatment.
To evaluate if a person has achieved a PR or CR, the doctor will perform tests before and during treatment.
These include measuring5:
- The size of certain organs
- The presence of symptoms
- Blood cell counts
To qualify for a PR, these measures are partially improved. For a CR, these measures are completely improved to normal.5,6
Make it a goal
Have You Talked With Your Doctor About MRD?
MRD stands for minimal residual disease. When someone has CLL, their doctor may use a highly sensitive test to measure the MRD in their blood or bone marrow. If MRD is found in the sample that is tested, it means that there are still CLL cells remaining. If no MRD is found, it's considered undetectable MRD (uMRD)—sometimes referred to as MRD negativity—which means CLL cells cannot be detected in the blood. uMRD is defined as having fewer than 1 cancer cell per 10,000 white blood cells.2,9
Interpreting results of MRD testing is complex. Due to limitations of MRD testing, there may still be cancer cells hidden in the body. It is not yet known whether making treatment decisions based on MRD status is beneficial, and some treatment options can provide a meaningful PFS and OS benefit even without achieving uMRD.10-12
Talk to your doctor to see if achieving uMRD may be a goal of your CLL treatment plan.
With treatment: detectable MRD
For some people who receive CLL treatment, cancerous B cells may be lessened but still detectable in the body.13